Only one or numerous drug overdose with oxycodone and acetaminophen can be a most likely lethal polydrug overdose, and session having a regional poison Command Heart is usually recommended.

The risk for serious breathing difficulties is better when you start this medication and after a dose maximize, or if you are taking the wrong dose/power. Using this medication with Alcoholic beverages or other medicines that could potentially cause drowsiness or respiratory challenges may well lead to very serious Unwanted effects, which includes Dying. Also, other prescription drugs can have an impact on the elimination of oxycodone/acetaminophen from the human body, which can have an affect on how it works.

Don't use with some other drug that contains acetaminophen without the need of asking your medical professional or pharmacist 1st. Acetaminophen is in several nonprescription and prescription medications (such as soreness/fever medications or cough-and-chilly products).

PERCOCET tablets should not be administered to clients with acknowledged hypersensitivity to oxycodone, acetaminophen, or some other element of the product or service.

Instruct individuals to search for acetaminophen or APAP on package labels rather than to use more than one products which contains acetaminophen. Instruct clients to seek professional medical consideration straight away upon ingestion of in excess of 4000 milligrams of acetaminophen on a daily basis, even whenever they sense nicely.

Clients need to be recommended that PERCOCET tablets are a potential drug of abuse. They need to secure it from theft, and it should really hardly ever be supplied to everyone aside from the person for whom it absolutely was prescribed.

Early indications pursuing a likely hepatotoxic overdose might incorporate: nausea, vomiting, diaphoresis, and basic malaise. Medical and laboratory proof of hepatic toxicity might here not be clear right until forty eight to seventy two several hours put up-ingestion.

Get this medication exactly as prescribed to reduced the chance of dependancy. Talk to website your physician or pharmacist For additional particulars.

The molecular components for oxycodone check here hydrochloride is C18H21NO4•HCl and the molecular weight 351.eighty two. It truly is derived with the opium alkaloid thebaine, and could be represented by the next structural formulation:

Opioid habit can cause major health concerns and may result in death. Read through much more on habit and the way to Stop.

In very low doses, acetaminophen could cause elevated liver enzymes. Using an excessive amount acetaminophen might cause liver destruction or liver failure. The risk of liver harm is bigger if you have already got liver complications, choose warfarin, or drink over 3 alcoholic beverages daily.

High doses of acetaminophen may perhaps deplete the glutathione merchants to ensure that inactivation with the toxic metabolite is lessened. At substantial doses, the capacity of metabolic pathways for conjugation with glucuronic acid and sulfuric acid may get more info very well be exceeded, causing improved metabolism of acetaminophen by alternate pathways.

Ordinarily, nursing really should not be undertaken whilst a affected individual is getting PERCOCET tablets thanks to the potential of sedation and/or respiratory melancholy in the infant.

Avoid consuming grapefruit or ingesting grapefruit juice while making use of this medication Unless of course your doctor or pharmacist states you might achieve this securely. Grapefruit can boost the potential for Negative effects using this medication. Question your health care provider more info or pharmacist For additional specifics.